Endocrine Abstracts

Background: Dopamine agonists (DA) have excellent result in controlling both hyperprolactinemia and tumor volume in macroprolactinomas. However, even after long term DA treatment, withdrawal of dopamine agonists results in recurrence of hyperprolactinemia in a significant proportion of patients.Aim: To assess recurrence rate of hyperprolactinemia after DA withdrawal in a large series of patients treated in a tertiar...

Background: Dopamine agonists (DA) have excellent result in controlling both hyperprolactinemia and tumor volume in macroprolactinomas. However, even after long term DA treatment, withdrawal of dopamine agonists results in recurrence of hyperprolactinemia in a significant proportion of patients.Aim: To assess recurrence rate of hyperprolactinemia after DA withdrawal in a large series of patients treated in a tertiar...

Background: PA is a frequent cause (5–13%) of secondary hypertension (HT), yet diagnostic work-up of PA remains challenging.Aim: To describe the characteristics of hypertensive patients diagnosed with PA, biochemical screening (aldosterone:renin ratio/ARR), confirmatory tests, and adrenal CT results.Methods: Clinical, hormonal and imaging evaluation.Results: 13 patients (7M/6F) with PA were 45 yrs (40&#1...

Introduction: PGs are rare neuroendocrine tumours (NETs), slowly growing, derived from the neural crest cells of the autonomous nervous system. Presenting symptoms are related to catecholamine hypersecretion or to mass effect. The optimal approach is dictated by size, symptoms and anatomical relationship of tumours with neurovascular structures.Aim: To describe a patient with bilateral carotid body and mediastinal carotid body PGs....

Background: PA is a clinical syndrome secondary to hemorrhage or infarction of pituitary tumour, presenting with sudden onset headache and oculomotor palsy. PA may be managed conservatively in patients without visual disturbances.Aim: To describe PA patients illustrating typical aspects and peculiarities.Results: Case 1, a 49 years old (yo) male, presented for loss of consciousness in the ER. MRI showed a giant pituitary tumour, wh...

Background: PBMAH is a rare cause of adrenal Cushing’s syndrome, frequently due to aberrant adrenal expression of hormonal receptors.Aim: To describe 6 patients with PBMAH.Methods: Clinical, hormonal and imagistic evaluation.Results: Age at diagnosis of patients (4M/2F) was 50–79 years. One asymptomatic patient was incidentally diagnosed on abdominal CT, two patients had overt Cushing’s (centra...

Background: PA is a frequent cause (5–13%) of secondary hypertension (HT), yet diagnostic work-up of PA remains challenging.Aim: To describe the characteristics of a series of hypertensive patients diagnosed with PA compared to those with negative biochemical screening (aldosterone-to-renin ratio/ARR)Methods: Clinical, hormonal and imaging evaluation.Results: We have screened for PA 34 patients diagnose...